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  • Title: Cystinosis and gingival hyperplasia: demonstration of cystine crystals in gingival tissue and unusual aspects of management.
    Author: Heller AN, Heller DS, Schwimmer A, Gordon RE, Cambria RJ.
    Journal: J Periodontol; 1994 Dec; 65(12):1139-41. PubMed ID: 7877086.
    Abstract:
    A patient with nephropathic cystinosis developed gingival hyperplasia secondary to cyclosporine-A therapy for his renal allograft. The typical crystals described on electron microscopic examination of other organs of patients with cystinosis were seen in the resected gingiva of this patient. These crystals have not been previously described in this location. Unusual aspects of the management of this patient are discussed.
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