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  • Title: [Epidemiologic study of immunologic status of confectionary workers].
    Author: Zuskin E, Kanceljak B, Mustajbegović J.
    Journal: Lijec Vjesn; 1994; 116(9-10):240-4. PubMed ID: 7885175.
    Abstract:
    Immunological and respiratory findings were studied in a group of 90 confectioners (mean age: 35 years; mean exposure: 11 years). Intradermal skin tests with different food allergens demonstrated the largest positive skin reaction to cocoa (63%), followed by chocolate (9%), cacao, nut and almond (6%) and sugar (2%). Increased IgE serum levels were found in 13.8% of the confectioners, and elevated IgM concentrations in 43.3%. The prevalence of occupational asthma and dyspnea (26.1%) in workers with positive skin tests was significantly higher than in those with negative skin tests (0%; 4.1%). There was a high prevalence of acute symptoms during the work shift. Most of these complaints were more frequent in workers with positive than in those with negative skin tests. Lung function studies demonstrated significant mean acute across-shift reductions of ventilatory capacity. Mean pre-shift FVC and FEF25 were significantly lower than predicted normal values. Pre-shift administration of disodium chromoglycate (DSCG) significantly diminished across-shift reductions for FEF50 and FEF25. Our data suggest that exposure to environmental factors in confectioneries may lead to immunological changes and the development of respiratory impairment in some workers.
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