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  • Title: Vasopressin inhibits food intake in pygmy goats by activation of alpha 1-adrenergic receptors.
    Author: Rossi R, Scharrer E.
    Journal: Pharmacol Biochem Behav; 1994 Dec; 49(4):897-900. PubMed ID: 7886104.
    Abstract:
    The hypophagic effect of intraperitoneally injected VP (1.5 micrograms/kg) was blocked by concomitant injection of the alpha 1-adrenergic antagonist prazosin (27 and 40 micrograms/kg). Both the alpha 2-adrenergic antagonists idazoxan (300 micrograms/kg) and yohimbine (500 micrograms/kg) and the beta-adrenergic antagonist propranolol (500 micrograms/kg) failed to block the hypophagia induced by VP (1.5 micrograms/kg). The results suggest that the hypophagic effect of VP is mediated by alpha 1-adrenergic receptors.
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