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Title: Synthesis and pharmacology of two new histamine receptor antagonists related to ranitidine. Author: Navarro JJ, Almeida JF, Anaya J, Moran JR, Grande M, Caballero MC, Palacios B, Montero MJ, San Roman L. Journal: Pharmazie; 1995 Jan; 50(1):12-5. PubMed ID: 7886119. Abstract: Pyridyl and 1,6-dihydropyridyl ranitidine analogues 1 and 2 were obtained by applying an improved modification of ranitidine synthesis. Compound 1 shows a selective H2 antagonistic activity while compound 2 is a non-selective histamine antagonist.[Abstract] [Full Text] [Related] [New Search]