These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Short term changes of cortical body maps following partial vibrissectomy in adult mice.
    Author: Siucińska E, Kossut M.
    Journal: Acta Neurobiol Exp (Wars); 1994; 54(4):345-54. PubMed ID: 7887185.
    Abstract:
    Vibrissae-to-barrels pathway is often used as a model for investigating CNS plasticity. We examined early changes in the cortical representation of row C of vibrissae in adult mice, following vibrissectomy removing all whiskers except row C. The changes of cortical representation of the spared row of vibrissae were mapped with 2-deoxyglucose autoradiography. We found that one day after lesion of vibrissal follicles the areal extent of cortical representation of row C is smaller than normally, but 7 days post lesion it increases significantly, by 60 to 90%, in all cortical layers. Additionally, seven days post-lesion the intensity of labelling was increased in cortical layer V. The result suggest that plasticity that can be observed with 2-deoxyglucose mapping in the barrel cortex is not due to unmasking of existing connection, but to reorganization of connectivity at many levels.
    [Abstract] [Full Text] [Related] [New Search]