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  • Title: Characterization of a promoter region supporting transcription of a novel human beta-galactoside alpha-2,6-sialyltransferase transcript in HepG2 cells.
    Author: Aas-Eng DA, Asheim HC, Deggerdal A, Smeland E, Funderud S.
    Journal: Biochim Biophys Acta; 1995 Mar 14; 1261(1):166-9. PubMed ID: 7893756.
    Abstract:
    In humans, two transcripts encoding beta-galactoside alpha-2,6-sialytransferase (EC 2.4.99.1.) have previously been described. One of the transcripts is widely expressed, whereas the other is restricted to mature B-cells. In this study we demonstrate the existence of a third transcript in the hepatoma cell-line HepG2. The expression of this transcript is controlled by a promoter region which efficiently supports transcription in HepG2 cells, and which harbours putative binding sites for liver-enriched and acute phase inducible transcription factors.
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