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  • Title: The role of protein kinase C in inducing Alzheimer's A68 protein expression in the culture of human neuroblastoma cells.
    Author: Zhang L.
    Journal: Neurosci Lett; 1994 Nov 07; 181(1-2):95-7. PubMed ID: 7898780.
    Abstract:
    By using the monoclonal antibody Alz50, we studied the role of protein kinase C (PKC) in inducing A68 protein expression in a human neuronal cell line. Both phorbol 12-myristate 13-acetate and H7 strongly induced A68 protein, while HA1004 and calphoslin C had no effect. The results suggest that the inhibitor and activator of PKC induce A68 protein expression by different mechanisms.
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