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  • Title: Collagenous colitis: a cause of chronic diarrhea.
    Author: Brady SK, McKee DD.
    Journal: Am Fam Physician; 1993 Nov 01; 48(6):1081-4. PubMed ID: 7901984.
    Abstract:
    Collagenous colitis should be added to the differential diagnosis of chronic, watery, nonbloody diarrhea with normal endoscopic findings. Patients with collagenous colitis are often middle-aged women previously diagnosed as having irritable bowel syndrome. The diagnosis of collagenous colitis is based on histologic evaluation of a rectal biopsy specimen. Biopsy shows a thickened, subepithelial, acellular, eosinophilic collagen band. Symptoms often resolve after treatment with oral sulfasalazine.
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