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  • Title: Identification of a new DNA polymorphism tightly linked to DQ-alpha locus.
    Author: Gasparini P, Bonizzato A, Totaro A, Zelante L.
    Journal: Exp Clin Immunogenet; 1993; 10(3):176-8. PubMed ID: 7904457.
    Abstract:
    Utilizing Alu-polymerase chain reaction and single-strand conformation polymorphism technologies a new DNA restriction fragment length polymorphism was detected on a cosmid clone located on chromosome 6p21. An accurate analysis of allele frequency was carried out on a large series of unrelated individuals. Furthermore a detailed linkage analysis in several large pedigrees showed this new polymorphism to be tightly linked to the HLA-DQ alpha locus.
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