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  • Title: Serum iron abnormalities in neuroleptic-induced akathisia in schizophrenic patients.
    Author: Soni SD, Tench D, Routledge RC.
    Journal: Br J Psychiatry; 1993 Nov; 163():669-72. PubMed ID: 7905347.
    Abstract:
    Twenty-two schizophrenic patients (DSM-III-R criteria) with clinically significant akathisia were matched with 22 schizophrenic patients without akathisia on the following variables: age, sex, diagnosis, duration of illness, and current treatment. Both groups were assessed using a variety of clinical rating scales and several parameters of serum iron status. The akathisic patients showed greater severity of clinical psychopathology, particularly positive symptoms, and an excess of extrapyramidal side-effects. We were unable to confirm any association between low serum iron and neuroleptic-induced akathisia in our sample of community-based patients.
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