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  • Title: Evaluation of a DUR intervention: a case study of histamine antagonists.
    Author: Zimmerman DR, Collins TM, Lipowski EE, Sainfort F.
    Journal: Inquiry; 1994; 31(1):89-101. PubMed ID: 7909535.
    Abstract:
    Drug Utilization Review (DUR) programs aim to control inappropriate prescribing and drug costs, but there are few rigorous studies of their impact. This paper presents the evaluation results of a DUR intervention (excessive duration of full-dose histamine-2 receptor antagonists) using a quasi-experimental design. We observe a greater reduction of H2RA use in the intervention group than in the comparison group, and a reduction in drug expenditures which exceeded the cost of targeting and notifying prescribers. The success of DUR programs depends on both their efficiency and the drug issues under consideration; the use of a comparison group is critical in the evaluation of their impact.
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