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  • Title: [Mitochondrial DNA RFLP in inhabitants of Magadan].
    Author: Maliarchuk BA, Lapinskiĭ AG, Balmysheva NP, Butorina OT, Solovenchuk LL.
    Journal: Genetika; 1994 Jan; 30(1):112-4. PubMed ID: 7910571.
    Abstract:
    Analysis of restriction fragment length polymorphism (RFLP) of mitochondrial DNA (mtDNA) from placenta tissue of Slavs living in Northern-East Asia is presented. BamHI, HpaI, EcoRV, and PvuII restriction endonucleases are used for this analysis (N = 40-50 for some restriction endonucleases). Combination of mtDNA types characteristic for distinct Mongoloid and Europeoid populations was found in a sample. HpaI-1 morph (Mongoloid marker) frequency is equal to 1.9% and BamHI-3 morph (Europeoid marker) frequency is equal to 2.5%. The sample investigated is monomorphic by PvuII endonuclease cleavage patterns. EcoRV-2 morph frequency exceeds 10%. Peculiarities of mtDNA restriction type structure in Magadan Region population are discussed in connection with a character of forming of Siberia and Far East population.
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