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  • Title: Arabidopsis ABA response gene ABI1: features of a calcium-modulated protein phosphatase.
    Author: Leung J, Bouvier-Durand M, Morris PC, Guerrier D, Chefdor F, Giraudat J.
    Journal: Science; 1994 Jun 03; 264(5164):1448-52. PubMed ID: 7910981.
    Abstract:
    The Arabidopsis ABI1 locus is essential for a wide spectrum of abscisic acid (ABA) responses throughout plant development. Here, ABI1 was shown to regulate stomatal aperture in leaves and mitotic activity in root meristems. The ABI1 gene was cloned and predicted to encode a signaling protein. Although its carboxyl-terminal domain is related to serine-threonine phosphatase 2C, the ABI1 protein has a unique amino-terminal extension containing an EF hand calcium-binding site. These results suggest that the ABI1 protein is a Ca(2+)-modulated phosphatase and functions to integrate ABA and Ca2+ signals with phosphorylation-dependent response pathways.
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