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  • Title: Comparison of thrombophlebitis associated with three cephalosporin antibiotics.
    Author: Siebert WT, Westerman EL, Smilack JD, Bradshaw MW, Williams TW.
    Journal: Antimicrob Agents Chemother; 1976 Sep; 10(3):467-9. PubMed ID: 791101.
    Abstract:
    A double-blind study with volunteers was performed to determine the incidence and severity of thrombophlebitis associated with cephalothin, cephapirin, cefamandole, and a water control. Although there were no statistical differences in the incidence of thrombophlebitis, cephalothin resulted in significantly more severe thrombophlebitis compared with the other agents.
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