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  • Title: [The pharmacokinetic characteristics of fenazepam in epileptics].
    Author: Maksutova EL, Sariev AK, Zherdev VP, Voronina TA, Zheleznova EV.
    Journal: Eksp Klin Farmakol; 1994; 57(2):16-8. PubMed ID: 7911365.
    Abstract:
    Testing the injectable dosage form of phenazepam showed no substantial pharmacokinetic differences in epileptic patients receiving a single intravenous and intramuscular doses of 2 mg. The bioavailability of the drug was 0.82. The individual and mean experimental stationary phenazepam concentration (157.3 ng/ml) in the patients' blood during course intramuscular therapy was found to be close to the theoretical stationary one (150.6 ng/ml). The pharmacokinetic findings allow one to optimize phenazepam therapy for epileptic patients.
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