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  • Title: Is antibiotic treatment of chronic sinusitis effective in children?
    Author: Otten HW, Antvelink JB, Ruyter de Wildt H, Rietema SJ, Siemelink RJ, Hordijk GJ.
    Journal: Clin Otolaryngol Allied Sci; 1994 Jun; 19(3):215-7. PubMed ID: 7923842.
    Abstract:
    A double-blind randomized controlled trial on 79 patients aged between 2 and 12 years with chronic sinusitis showed no significant advantage of adding antibiotics to the treatment by sinus lavage. The prognosis after both 6 and 12 weeks was worse for patients with bilateral opaque sinus radiographs. Half of the Branhanmella catarrhalis cultured in this study were beta-lactamase producing organisms, therefore antibiotics prescribed for this group of children should be chosen bearing this in mind.
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