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Title: Refined mapping of the human Ets-related gene Elk-1 to Xp11.2-p11.4, distal to the OATL1 region. Author: Janz M, Lehmann U, Olde Weghuis D, de Leeuw B, Geurts van Kessel A, Gilgenkrantz S, Hipskind RA, Nordheim A. Journal: Hum Genet; 1994 Oct; 94(4):442-4. PubMed ID: 7927346. Abstract: The gene for human Elk-1, an Ets-related transcription factor, has previously been localized to a region that lies on the short arm of chromosome X and that is involved in specific chromosomal translocations associated with synovial sarcoma and renal adenocarcinomas. We have used fluorescence in situ hybridization and a panel of tumor-derived somatic cell hybrids to refine the localization of Elk-1, in particular with regard to the rearrangements in these tumors. Elk-1 has been assigned to Xp11.2-p11.4, distal to the OATL1 region.[Abstract] [Full Text] [Related] [New Search]