These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: A seroepidemiological study of human immunodeficiency virus infection in northeast Zaire.
    Author: Bernal MC, Galán MI, Ocete MD, Leyva A, García F, García-Valdecasas J, Maroto MC, Piédrola G.
    Journal: Infection; 1994; 22(3):174-7. PubMed ID: 7927812.
    Abstract:
    To evaluate the incidence of human immunodeficiency virus type 2 infections in an endemic African area, we have studied 134 patients from Northeast Zaire. Sera were tested for HIV-1 and HIV-2 antibodies to asses cross-reactivity or a possible double infection. Sixty five (48.5%) serum samples were reactive for HIV-1 and six (4.5%) for HIV-2 using specific Western blots. The enzyme immunoassays used to detect HIV-2 showed cross-reactivity with HIV-1 in 17 samples (16.5%). Tests based upon synthetic peptides corresponding to specific from human immunodeficiency viruses confirm their ability to discriminate antibodies directed against both viruses in 42/47 samples (89.4%); in 5/47 (10.6%) this test could not distinguish double infection from cross-reactivity. We suggest that the high number of sexual partners may be responsible for HIV transmission in our study group. To evaluate the incidence of human immunodeficiency virus type 2 infections in an endemic African area, the authors have studied 134 patients from Northeast Zaire. Sera were tested for HIV-1 and HIV-2 antibodies to assess cross-reactivity or a possible double infection. 65 (48.5%) serum samples were reactive for HIV-1 and 6 (4.5%) for HIV-2 using specific Western blots. The enzyme immunoassay used to detect HIV-2 showed cross-reactivity with HIV-1 in 17 samples (16.5%). Tests based upon synthetic peptides corresponding to specific glycopeptides from human immunodeficiency viruses confirm their ability to discriminate antibodies directed against both viruses in 42/47 samples (89.4%); in 5/47 (10.6%) this test could not distinguish double infection from cross-reactivity. The authors suggest that the high number of sexual partners may be responsible for HIV transmission in this study group. (author's)
    [Abstract] [Full Text] [Related] [New Search]