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  • Title: Chronic methemoglobinemia: improving hemoglobin saturation monitoring during anesthesia.
    Author: Sprung J, Bourke DL, Mackenzie CF, Thomas P.
    Journal: J Clin Monit; 1994 Jul; 10(4):267-9. PubMed ID: 7931458.
    Abstract:
    Methemoglobin interferes with the accuracy of pulse oximetry data. Methemoglobinemia is caused by many factors, both congenital and acquired. However, the increasing usage of dapsone, which converts hemoglobin to methemoglobin, is increasing the number of patients with methemoglobinemia. We present the case of a patient with dapsone-induced methemoglobinemia who was successfully treated with methylene blue, which converts methemoglobin back to hemoglobin.
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