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  • Title: Persistent polyclonal B-cell lymphocytosis.
    Author: Agrawal S, Matutes E, Voke J, Dyer MJ, Khokhar T, Catovsky D.
    Journal: Leuk Res; 1994 Oct; 18(10):791-5. PubMed ID: 7934138.
    Abstract:
    We document a case of persistent lymphocytosis in which the characteristic binucleated circulating lymphocytes were shown immunologically to be polyclonal B-cells. Cytogenetic and molecular studies failed to show a clonal population. A review of the literature on this rare condition, persistent polyclonal B-cell lymphocytosis, highlights an association with the female sex, HLA-DR7 antigen, smoking and raised levels of IgM, all of which were present in our patient.
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