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  • Title: [Microangiopathic hemolytic anemia associated with neoplasms: an analysis of 5 cases and a review of the literature].
    Author: Susano R, Caminal L, Ferro J, Rubiales A, de Lera J, de Quirós JF.
    Journal: Rev Clin Esp; 1994 Aug; 194(8):603-6. PubMed ID: 7938839.
    Abstract:
    From January of 1990 to June of 1993 a diagnosis of microangiopathic hemolytic anemia (MHA) was made in 5 out off 121 new patients with malignant tumor. There were 3 females and 2 males, with a mean age of 57 yr (range: 43-75), and a primary tumor in stomach (n = 2), pancreas (n = 1) and of unknown origin (n = 2). In all cases histologic type was adenocarcinoma and diagnosis was obtained by marrow examination. Four patients developed a disseminated intravascular coagulation syndrome. Intravascular deposits of fibrin, intimal proliferation and tumoral microembolisms were noted in 2 cases. Patients did not received chemotherapy, and the median survival was 7 days (range: 3-61).
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