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  • Title: Indirect immunofluorescence assay for antibody to germ tube of Candida albicans--a new diagnostic test.
    Author: Ho YM, Ng MH, Teoh-Chan CH, Yue PC, Huang CT.
    Journal: J Clin Pathol; 1976 Nov; 29(11):1007-10. PubMed ID: 794079.
    Abstract:
    Indirect immunofluorescent and agglutination assay were used to study the anti-Candida albicans reactivities in the serum of 13 normal subjects and 14 patients infected with C. albicans. A significant increase in anti-C. albicans seroreactivity was observed during infection with this organism but the increase in the anti-germ tube immunofluorescence titre was the more marked. It is evident that the anti-germ tube immunofluorescence assay is more discriminatory for C. albicans infection than the conventional agglutination assay.
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