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  • Title: [Analysis of the dopamine D2 receptor gene].
    Author: Arinami T, Itokawa M.
    Journal: Nihon Shinkei Seishin Yakurigaku Zasshi; 1994 Jun; 14(3):129-37. PubMed ID: 7941777.
    Abstract:
    The methods, such as Southern blot hybridization, PCR-direct sequencing and PCR-SSCP, to detect sequence variants in the human dopamine D2 receptor (DRD2) gene were described. To study the association of a missense variant of the DRD2 gene resulting in Ser311-->Cys, which was detected by PCR-direct sequencing in schizophrenics, the genotypes of controls and schizophrenics were determined by the methods of PCR-dot blot hybridization, PCR amplification of specific alleles and artificially introduced PCR-RFLP.
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