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  • Title: The value of complement fixation and haemagglutination inhibition tests in the diagnosis of influenza A.
    Author: Pyhälä R, Kleemola M.
    Journal: Acta Virol; 1976 Feb; 20(1):66-9. PubMed ID: 7943.
    Abstract:
    Antibody response of 133 influenza A patients from three outbreaks since 1972-73 was analyzed by complement fixation (CF) and haemagglutination inhibition (HI) methods. During the first outbreak, a significant response was more often measured by CF than by HI. During the last outbreak HI appeared more useful than CF for routine serological diagnosis; 23% of cases verified by HI were missed by CF. The poor response of CF antibodies was associated with the high level of pre-infection antibodies.
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