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  • Title: Synthesis and biological evaluation of derivatives of N-[4-substituted-1-piperazinylalkyl]-1-(butyl,aryl)-2,5- dimethylpyrrole-3,4-dicarboxymide (Part II).
    Author: Malinka W, Sieklucka-Dziuba M, Robak J, Kleinrok Z.
    Journal: Farmaco; 1994; 49(7-8):481-7. PubMed ID: 7945713.
    Abstract:
    A series of new N-[4-substituted-1-piperazinyl-alkyl]-3,4-pyrroledicarboxyimides 7 have been prepared by reaction of N-haloalkylimide derivatives 6 with corresponding N-monosubstituted piperazines. Compounds 7 tested in preliminary pharmacological investigation produced a general depressive action on the central nervous system.
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