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  • Title: Synthesis and in vitro anti-HIV activity of novel delta 2-1,2,4-oxadiazoline derivatives.
    Author: Chimirri A, Grasso S, Monforte AM, Monforte P, Zappalà M, Carotti A.
    Journal: Farmaco; 1994; 49(7-8):509-11. PubMed ID: 7945718.
    Abstract:
    The synthesis of 4-adamantyl-5-aryl-3-phenyl-delta 2-1,2,4-oxadiazolines, involving an 1,3-dipolar cycloaddition reaction between 1-[(arylidene)amino]adamantanes and benzonitriloxide, is described. The evaluation of in vitro antiviral activity against human immunodeficiency virus (HIV) of the compounds obtained is also reported.
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