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  • Title: Dynamic MR mammography: a technique for potentially reducing the biopsy rate for benign breast disease.
    Author: Turkat TJ, Klein BD, Polan RL, Richman RH.
    Journal: J Magn Reson Imaging; 1994; 4(4):563-8. PubMed ID: 7949682.
    Abstract:
    Thirty-five women with a total of 39 breast lesions detected at mammography and/or physical examination and who were scheduled for surgical biopsy were studied with dynamic magnetic resonance (MR) mammography. Fat-suppressed, spoiled GRASS (gradient-recalled acquisition in the steady state) sequences were performed before and after administration of gadopentetate dimeglumine. T1-weighted spin-echo and fat-suppressed T2-weighted fast spin-echo images were also obtained. By measuring percentage signal intensity change in lesions on the spoiled GRASS images after contrast agent injection, the authors achieved a sensitivity of 100% and a specificity of 83.3% in differentiating benign from malignant lesions (24 benign, 15 malignant), with biopsy results as the standard. This dynamic MR mammography technique deserves further evaluation.
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