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  • Title: [Treatment of impotence with intracavernous auto-injections: moxisylyte diminishes the risks compared to papaverine].
    Author: Buvat J, Buvat-Herbaut M, Lemaire A, Marcolin G.
    Journal: Contracept Fertil Sex; 1993 Feb; 21(2):173-6. PubMed ID: 7951610.
    Abstract:
    The alpha-blocking agent Moxisylyte was tested in auto-intracavernous injections (auto-ICI) in 72 impotent patients. The side-effects were compared to those observed in a group of 34 impotent patients treated with auto-ICI of Papaverine during the same period of time. The Moxisylyte auto-ICI improved 83% of the patients including 68% reporting a complete and durable success. Moxisylyte proved to be safer due to a reduced rate of prolonged erections (1.3% of the patients versus 8.8% with Papaverine) and corporeal fibrosis (1.3% versus 32% with Papaverine). Though less potent than Papaverine, and often seeming insufficient when tested in the office, this type of alpha-blocking agent could be tried in a first time in most candidates to auto-ICI before resorting to Papaverine or Prostaglandin E1 if it fails.
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