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  • Title: [Bowen's disease and bowenoid papulosis: comparative clinical, viral, and disease progression aspects].
    Author: de Belilovsky C, Lessana-Leibowitch M.
    Journal: Contracept Fertil Sex; 1993 Mar; 21(3):231-6. PubMed ID: 7951618.
    Abstract:
    Among the VIN (vulvar intraepithelial neoplasia), it is necessary to distinguish the classical Bowen's disease (CBD) and bowenoid papulosis (BP). This retrospective study concerning 75 VIN (36 CBD and 39 BP) demonstrated that the most efficient criteria are the clinical aspect and the age of the onset (CBD = 55.6 years old; BP = 33.2 years old). BP is clinically related to genital warts (41 cases). They share the same age of onset, the fact to be sexually transmitted diseases and the benign evolution. Although virological results between CBD and BP are very similar (human papilloma virus type 16, 18, 31, 33), the development of an invasive carcinoma is mostly related to the CBD (27.8%) and is exceptional in the BP (2.6%).
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