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  • Title: Chromosome abnormalities in breast fibroadenomas.
    Author: Ozisik YY, Meloni AM, Stephenson CF, Peier A, Moore GE, Sandberg AA.
    Journal: Cancer Genet Cytogenet; 1994 Oct 15; 77(2):125-8. PubMed ID: 7954322.
    Abstract:
    Cytogenetic analysis of 25 breast fibroadenomas (FA) showed clonal chromosome alterations in three cases. Insertion (12;?) (q15;?) and deletion (2) (q14q31 or q32) were detected as a sole change in cases 1 and 3, respectively. Case 2 displayed the karyotype 45,XX,t(1;8;16)(q25;q23;q22-23), add (7)(p14), rea(15), -17. The present findings are discussed together with the reports on FA in the literature.
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