These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The effect of 'conditioning' exposures on hearing loss from impulse noise.
    Author: Henselman LW, Henderson D, Subramaniam M, Sallustio V.
    Journal: Hear Res; 1994 Jul; 78(1):1-10. PubMed ID: 7961172.
    Abstract:
    Research has shown that prior noise exposures or 'conditioning' can moderate the amount of permanent threshold shift (PTS) from subsequent high intensity noise exposures. The aim of this experiment was to study the effect of 'conditioning' on subsequent exposure to high intensity impulse noise. The subjects were seven experimental and 14 control monaural chinchillas. Evoked potential (EVP) thresholds were measured before and after the noise exposures. Experimental animals received 10 days of exposure to an octave band noise (OBN) centered at 0.5 kHz OBN at 95 dB SPL (6 h on/18 h off) and allowed to recover for 5 days. The subjects were then exposed to an impulse noise at 150 dB SPL. The temporal spacing of the impulses consisted of a series of 50 pairs of impulses presented 50 ms apart with 1000 ms between the onset of each pair. The total duration of exposure was approximately 1 min. Control animals received only the impulse noise exposure. PTS was measured after 4 weeks. The threshold shift (TS) patterns during the 'conditioning' phase were consistent with previous research, with the greatest amount of TS occurring on the second day and decreasing with continued exposures. Four weeks after recovery from the impulse noise, the experimental animals showed significantly less PTS than the control animals. In addition, histological examination revealed significantly less hair cell loss in the experimental than in the control subjects. The results are discussed in the context of previous studies on 'toughening' and on the effects of impulse noise.
    [Abstract] [Full Text] [Related] [New Search]