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  • Title: Nosocomial transmission of an avian-like rotavirus strain among children in Belém, Brazil.
    Author: Gusmão RH, Mascarenhas JD, Gabbay YB, Linhares AC.
    Journal: J Diarrhoeal Dis Res; 1994 Jun; 12(2):129-32. PubMed ID: 7963343.
    Abstract:
    An atypical group-A rotavirus strain, with an electrophoretype displaying 5 segments in the first dsRNA size class, was detected among 3 hospitalized children less than 2 years old. Detection occurred initially 24 h after admission in a non-diarrhoeic child hospitalized because of acute respiratory infection. The second detection involved a child who occupied a different room within the same ward and who developed nosocomial diarrhoea 48 h later. A third case, also of hospital-acquired diarrhoea, was recorded in a child who occupied a bed in the same room as the second case and developed gastroenteritis 24 h following the second case's detection. In addition to the unusual, avian-like genomic profile, the strain was classified as serotype 2, based on a human VP7-specific enzyme-linked immunosorbent assay (ELISA). The question of whether these events reflect either a genomic rearrangement of a human rotavirus strain or a possible interspecies transmission will be further investigated through hybridization assays.
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