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  • Title: Rate of occurrence of Helicobacter pylori in patients with gastroduodenal pathology: pilot research.
    Author: Nicosia R, Pustorino R, Sessa R, Santino I, Busicchio P, D'Ambra GC, Di Paola M, Del Piano M.
    Journal: New Microbiol; 1994 Jul; 17(3):217-23. PubMed ID: 7968657.
    Abstract:
    In an attempt to establish the etiologic role of Helicobacter pylori (H. pylori) in gastric and/or duodenal pathology, 169 patients were tested and compared with a control group of 25 healthy subjects, for a total of 194 subjects. Data on sex, age, familiarity, smoking, coffee and alcohol habits were collected and each patient underwent histological, microbiological and immunological tests. 80 (41.2%) subjects were found positive to H. pylori. This bacterium was detected in 53.3% of patients with gastric ulcer while IgG were found in 86.7%; in 50% of patients with chronic atrophic gastritis while IgG were detected in 80%; in 48.5% of patients with duodenal ulcer while IgG were found in 87.9%; in 41.8% of patients with superficial chronic gastritis while IgG were detected in 80.2%. In the control group of healthy patients H. pylori was found in 28% of patients while IgG were detected in 62.5%. The results do not confirm a direct clear-cut correlation between this microorganism and the pathologies studied.
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