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  • Title: [Effect of xenotransplantation of islet cell culture on the course of alloxan diabetes in rats fed a diet varying in protein content].
    Author: Sadykova RE, Skaletskiĭ NN, Dreval' AV, Kirsanova LA, Shishko PI.
    Journal: Probl Endokrinol (Mosk); 1994; 40(4):45-7. PubMed ID: 7971911.
    Abstract:
    The authors present data on the protective effect of newborn rabbits pancreatic islet cell culture xenotransplantation of Langerhans' islet beta-cells of rats with alloxan diabetes. This effect was the most marked in rats fed diets with normal or increased protein content. The authors discuss a possible stimulating effect of rabbit islet cell culture xenotransplantation on regeneration processes in recipient rat pancreatic islets. This effect was better pronounced in rats kept on rations with increased protein content. Further experiments will help more accurately define the indications for therapy of insulin-dependent diabetes mellitus by xenotransplantations of islet cell cultures.
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