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  • Title: [Determination of the excretion time of oxytetracycline and lugol in milk of intrauterine treated cows].
    Author: Dijkstra T, Barkema HW, van Buuren RD, van Spanje JG, Jorritsma H.
    Journal: Tijdschr Diergeneeskd; 1994 Nov 01; 119(21):634-6. PubMed ID: 7974451.
    Abstract:
    Sixteen dairy cows with chronic puerperal endometritis between 3 and 8 weeks post partum were treated with intra-uterine applied oxytetracycline (OTC) and lugol. OTC was rapidly removed from plasma and was not detectable after 48 hours. The concentration of OTC in milk did not exceed 40 micrograms/kg, and it was still detectable in milk 34 hours after treatment. The concentration of OTC in milk was always lower than the limit of 50 micrograms/kg used by milk-testing stations and the European limit (MRL) of 100 micrograms/kg. Milk from cows treated with lugol did not cause inhibition in the plate test.
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