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  • Title: [Plexiform fibrohistiocytic tumor].
    Author: Sass U, André J, Noël JC, Larsimont D, Olemans C, de Dobbeleer G, Wanet J, Ledoux M.
    Journal: Ann Dermatol Venereol; 1994; 121(2):109-12. PubMed ID: 7979015.
    Abstract:
    Plexiform fibrohistiocytic tumour has been recently described by Enzinger and Zhang. This is a rare tumour with low grade malignancy which requires large excision. We report two cases, one occurring in a 58-year-old man, presenting a voluminous painless mass of 5 cm on his hand, the other occurring in a 9-year-old boy consulting for a nodule on the chest. On histological examination this dermal hypodermal tumour is characterized by a proliferation of histiocytic-like cells grouped in nodules, where they are associated with multinucleated osteoclastic-like cells and a proliferation of fibroblastic-like cells grouped in fascicles, anastomosing in a plexiform pattern. Immunohistochemistry and ultrastructural aspects are described. Differential diagnosis and histogenesis are discussed.
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