These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Inflammatory pseudotumor of the ileum. A report of a multifocal, transmural lesion with regional lymph node involvement.
    Author: Myint MA, Medeiros LJ, Sulaiman RA, Aswad BI, Glantz L.
    Journal: Arch Pathol Lab Med; 1994 Nov; 118(11):1138-42. PubMed ID: 7979901.
    Abstract:
    Inflammatory pseudotumor (inflammatory fibroid polyp) of the ileum is a rare, usually solitary and polypoid lesion that frequently presents clinically as small-intestinal intussusception and obstruction. Regional lymph nodes are usually not involved. We describe an inflammatory pseudotumor of the ileum that was multifocal, not polypoid, and involved one regional lymph node. Grossly, two circumferential transmural nodules were separated by 8.5 cm of normal ileum. Microscopically, the lesion extended through the muscularis propria into peri-intestinal adipose tissue and involved one noncontiguous regional lymph node. The pseudotumor was composed of highly vascularized stroma with a mixture of spindle cells and chronic inflammatory cells including numerous eosinophils, lymphocytes, plasma cells, histiocytes, neutrophils, and multinucleated giant cells forming small granulomas. Immunohistochemically, the majority of spindle cells reacted with vimentin but not smooth-muscle, endothelial, or lymphoid markers. Ultrastructurally, the spindle cells had abundant rough endoplasmic reticulum, cytoplasmic filaments, and dense bodies consistent with myofibroblasts, plump endothelial cells (some with Weibel-Palade bodies), and chronic inflammatory cells. We prefer the term inflammatory pseudotumor to inflammatory fibroid polyp for the lesion in this case, since it was not polypoid and shared many histologic features with inflammatory pseudotumors arising at sites other than the gastrointestinal tract.
    [Abstract] [Full Text] [Related] [New Search]