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  • Title: [Chronic placental insufficiency and histogenesis of fetal thyroid in late spontaneous abortions].
    Author: Stepanov SA, Kirichenko AK, Aleskeev IA.
    Journal: Arkh Patol; 1993; 55(1):64-8. PubMed ID: 7980045.
    Abstract:
    The role of chronic placental insufficiency in the ontogenetic maturation of fetal thyroid gland was studied in 75 cases. The second trimester of physiologically normal and complicated by premature delivery pregnancies showed correlations between organometric and histiostereometric indices of placenta and thyroid gland. In case of chronic placental insufficiency depression of placental metabolic processes was found associated with discoordination of histogenesis of fetal thyroid gland, a decrease of specific capacity of its parenchyma and vessels, as well as with growth of stroma component value. These prove reduced histiofunctional properties and adaptive reactions of placenta.
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