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  • Title: Myoglobinuric acute renal failure in a cardiac transplant patient taking lovastatin and cyclosporine.
    Author: Alejandro DS, Petersen J.
    Journal: J Am Soc Nephrol; 1994 Aug; 5(2):153-60. PubMed ID: 7993994.
    Abstract:
    Acute renal failure can occur in cardiac transplant patients for a variety of reasons. A case of a patient who developed acute renal failure secondarily to drug-induced rhabdomyolysis is reported. The literature regarding acute renal failure and lovastatin and other 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors is reviewed. The potential mechanisms of myoglobinuria and nephrotoxicity and the therapeutic implications are discussed.
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