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  • Title: Tricyclic heteroaromatic systems. 2-Phenyl-1,2,4-triazolo[1,5-c][1,3]benzoxazin-5-one: a novel benzodiazepine receptor ligand.
    Author: Catarzi D, Cecchi L, Colotta V, Filacchioni, Martini C, Giusti L, Lucacchini A, Valle G.
    Journal: Farmaco; 1994 Feb; 49(2):89-92. PubMed ID: 8003185.
    Abstract:
    The synthesis, unambiguous proof of structure and benzodiazepine receptor affinity and efficacy of 2-phenyl-1,2,4-triazolo[1,5-c][1,3]benzoxazin-5-one 1 are reported. The in vitro biological data indicate that 1 may be the lead compound of a new class of benzodiazepine antagonist-inverse agonist ligands.
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