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  • Title: [Interstitial pneumonia in patients with human T-cell lymphotropic virus type-1 infection].
    Author: Sugimoto M.
    Journal: Nihon Kyobu Shikkan Gakkai Zasshi; 1993 Dec; 31 Suppl():36-41. PubMed ID: 8007471.
    Abstract:
    Pulmonary involvement has been demonstrated in patients with human T-cell lymphotropic virus type-1 (HTLV-1)-associated myelopathy (HAM/TSP) or with HTLV-1 uveitis. Pulmonary lesions in these patients are characterized by T-lymphocyte alveolitis. Interestingly, HLTV-1-infected cells were markedly increased in bronchoalveolar lavage fluid (BALF) obtained from patients with HAM/TSP and those with HTLV-1 uveitis compared to asymptomatic HTLV-1 carriers. Furthermore, the proportion of HTLV-1-infected cells was much higher in BALF than in peripheral blood. These results suggest that increased HTLV-1-infected cells play an important role in evolution of T-lymphocyte alveolitis associated with HTLV-1 infection.
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