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  • Title: Red blood cell sodium-lithium countertransport in patients with essential and renal hypertension.
    Author: Petrov VV, Arabidze CG, Levitsky DO, Eliseev AO, Lijnen PJ.
    Journal: Methods Find Exp Clin Pharmacol; 1994 Mar; 16(2):153-7. PubMed ID: 8007744.
    Abstract:
    The erythrocyte Na+/Li(+)-countertransport activity was studied in patients with essential hypertension (n = 59), chronic glomerulonephritis (n = 30), chronic pyelonephritis (n = 26), renovascular hypertension (n = 35) and pheochromocytoma (n = 3). The erythrocyte Na+/Li(+)-countertransport (SLC) activity was on average higher (p < 0.02) in the patients with essential hypertension as compared to those with secondary hypertension, although a clear distinction between both groups was not possible. After surgical treatment of the patients with atherosclerotic renal artery stenosis, fibromuscular dysplasia or pheochromocytoma, no change in erythrocyte SLC activity was observed. However, blood pressure was significantly reduced.
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