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  • Title: [Synthesis and antibacterial activities of 1-amino-6-fluoro-1,4-dihydro-4-oxo-7-(substituted) piperazinyl-3-quinolinecarboxylic acids and their derivatives].
    Author: Xin T, Ding J, Zhang XP.
    Journal: Yao Xue Xue Bao; 1993; 28(11):865-9. PubMed ID: 8010004.
    Abstract:
    The title compounds 6-24 were obtained by the reaction of 5 with corresponding benzaldehydes. 5 was prepared with ethyl 7-chloro-6-fluoro-1,4-dihydro-4-oxo-3- quinolinecarboxylate by hydrolysis, amination and condensation with piperazine. Anti-bacterial activities of 5-24 were tested in vitro.
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