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  • Title: Transient severe brain stem depression during intraarterial papaverine infusion for cerebral vasospasm.
    Author: Barr JD, Mathis JM, Horton JA.
    Journal: AJNR Am J Neuroradiol; 1994 Apr; 15(4):719-23. PubMed ID: 8010275.
    Abstract:
    A 63-year-old woman had severe, symptomatic cerebral vasospasm secondary to subarachnoid hemorrhage. We initiated simultaneous infusions of papaverine into her left vertebral and left internal carotid arteries. Twenty-five minutes after the infusions had begun, the patient had a transient reaction of respiratory arrest followed by rapid, progressive loss of brain stem function.
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