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  • Title: Interactions of polyamines in the measurement of free magnesium concentration by mag-fura-2 and 31P-NMR.
    Author: Günther T, Vormann J, Konstanczak P, Schäfer A.
    Journal: Biochim Biophys Acta; 1994 Jun 22; 1192(2):281-5. PubMed ID: 8018709.
    Abstract:
    Polyamines, particularly spermine, in physiological concentrations interact with mag-fura-2 and the mag-fura-2/Mg2+ complex, resulting in reduced values of free Mg2+ concentration. Similarly, polyamines interact with ATP and MgATP. Thus, free Mg2+ concentration, as measured by 31P-NMR or mag-fura-2, is underestimated in the presence of polyamines, particularly of spermine.
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