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  • Title: [The participation of cardioactive peptides in the processes of habituation and sensitization of the synaptic input to the command neurons in snail defensive behavior].
    Author: Bravarenko NI.
    Journal: Zh Vyssh Nerv Deiat Im I P Pavlova; 1994; 44(2):301-6. PubMed ID: 8023570.
    Abstract:
    Small cardioactive peptide (SCPb) application in a concentration of 5 x 10(-8) M in the saline results in a significant increase of the amplitude of the summary excitatory postsynaptic potential elicited by the intestinal nerve stimulation in the command neurons (CN) for withdrawal reactions. Serotonin (5-HT) exerts comparable effects in a concentration of 10(-6) M. FMRFamide application (10(-6) M) significantly decreases the amplitude of the synaptic response to a single stimulus. Habituation rate of synaptic responses to the rhythmic (0.1 cps) stimulation in CN is significantly increased by serotonin application. SCPb acts in a similar fashion but in a lower concentration. FMRFamide application in a concentration of 10(-6) M affects in the opposite way the habituation rate of synaptic responses to rhythmic stimulation and in some cases evokes sensitization of responses.
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