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  • Title: A case of pulmonary amyloidosis associated with multiple myeloma successfully treated with dimethyl sulfoxide.
    Author: Iwasaki T, Hamano T, Aizawa K, Kobayashi K, Kakishita E.
    Journal: Acta Haematol; 1994; 91(2):91-4. PubMed ID: 8023651.
    Abstract:
    A 57-year-old man with IgG multiple myeloma developed pulmonary infiltration caused by pulmonary amyloidosis, for which continuous transdermal dimethyl sulfoxide (DMSO) treatment was given. After 8 weeks from the start of DMSO treatment, a dramatic reduction of pulmonary infiltration as determined by chest roentgenogram was observed, and arterial blood gas levels were improved. No serious side effect of DMSO was encountered. We conclude that a therapeutic trial with transdermal DMSO administration brought about a marked regression of the pulmonary infiltrate.
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