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  • Title: Expanding horizons for receptors coupled to G proteins: diversity and disease.
    Author: Coughlin SR.
    Journal: Curr Opin Cell Biol; 1994 Apr; 6(2):191-7. PubMed ID: 8024809.
    Abstract:
    The known repertoire of seven transmembrane domain receptors coupled to G proteins has expanded in several interesting directions. Both loss-of-function and activating mutations have been found at the root of a variety of diseases. More will undoubtedly be uncovered. The diversity of ligands which trigger G protein coupled receptors continues to grow, and with it the variety of known strategies for ligand detection. These and other developments promise continued excitement in this field.
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