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  • Title: The effect of tolazoline on right-to-left shunting via a patent ductus arteriosus in meconium aspiration syndrome.
    Author: Levin DL, Gregory GA.
    Journal: Crit Care Med; 1976; 4(6):304-7. PubMed ID: 803084.
    Abstract:
    Since arterial blood oxygen tensions are used in the evaluation of treatment of patients with meconium aspiration syndrome, it is important to recognize the occurrence of significant right-to-left shunting via a patent ductus arteriosus. The clinical findings, evidence of right-to-left ductus shunting, and outcome in eight patients with meconium aspiration syndrome are presented. Administration of tolazoline HCl and curare produced a beneficial effect on their PaO2 values.
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