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  • Title: Assessment of cysteinyl leukotriene synthesis in man.
    Author: Frölich JC, Fauler J, Tsikas D.
    Journal: J Lipid Mediat Cell Signal; 1994 Feb; 9(1):75-8. PubMed ID: 8032717.
    Abstract:
    We have developed methods to measure LTE4, the index metabolite of cysteinyl leukotrienes, by HPLC/RIA and GC/MS. Urinary LTE4 appears to be a reliable parameter to assess whole body cysteinyl leukotriene synthesis in man from all evidence available at this time. Measurement of this metabolite can be used to monitor effects of diseases and drugs on cysteinyl leukotriene synthesis in man.
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